2008 Conference Presentations

Select presentations from the conference can be accessed by clicking on the “PDF” links below.  Please note: some presentations may have been modified to remove unpublished data.

 

September 21

Keynote Lecture
Mario Raviglione, Stop TB Department, World Health Organization
- Tuberculosis is a global health issue: challenges and need for new tools

 

September 22

Session 1: Pathogen and host biology (I)

*Douglas Young, Imperial College London
- The diversity of latent TB

Markus Wenk, National University of Singapore
Lipidomics in biomarker development

Sebastien Gagneux, MRC National Institute for Medical Research
Evolutionary forces in Mycobacterium tuberculosis: Implications for product development

JohnJoe McFadden, University of Surrey
Systems approaches to uncovering in vivo state of the TB bacillus

Steven Elledge, Harvard University
A Functional Genomics Approach to Viral-Host Interactions for HIV

Session 2: Pathogen and host biology (II)

*Stefan Kaufmann, Max Planck Institute for Infection Biology
Host response to tuberculosis as basis for rational design of vaccines and biomarkers

T. Mark Doherty, Statens Serum Institut
- Separating latent and acute TB

Padmini Salgame, University of Medicine and Dentistry of New Jersey
Probing the mechanisms that regulate mycobacterial Th1 immunity

Marila Gennaro, Public Health Research Institute, University of Medicine and Dentistry of New Jersey
- Genome-scale antibody responses in TB

Muireann Coen, Imperial College London
Translation of Metabolite Profiling to Infectious Diseases

Late Breakers

Joshua Mattila
Early immunologic events in cynomolgus macaques coinfected with Mycobacterium tuberculosis and a pathogenic siman immunodeficiency virus

Melissa Nyendak
The diagnostic potential of the CD8+ T cell response: tracking intracellular infection with Mycobacterium tuberculosis

Hugh Salamon
Statistical pathway analysis of antibody responses to the Mycobacterium tuberculosis proteome reveals molecular features of active infection in patients

Martin Vordermeier
Using murine global gene expression analysis to predict biomarkers of protective immunity in cattle: A role for IL-17 producing cells in protective immunity?

 

September 23

Session 3: The child's immune system and pediatric tuberculosis

Joe Bellanti, Georgetown University Medical Center
The child's immune system and pediatric tuberculosis

*Anneke Hesseling, Stellenbosch University
- Pediatric tuberculosis: clinical and epidemiological reflections from a highly endemic setting

Session 4: Field studies and clinical trials: present and future

*Dick Menzies, McGill University
- Evaluating new diagnostic tests in the field – are we doing it right?

Sandra Arend, Leiden University Medical Center
- A specific skin test; the best for both worlds?

Peter Andersen, Statens Serum Institut
IGRA based diagnosis of infection and prediction of disease

Session 5: New strategies for immunodiagnosis (I)

Mark Perkins, Foundation for New and Innovative Diagnostics
TB immunodiagnosis in context of global disease care and control

*Philip Felgner, University of California, Irvine
Profiling the Immune Response to TB Infection on a Genome-Wide Scale with Protein Microarrays

Session 6: New strategies for Immunodiagnosis (II)

*Mario Roederer, National Institute of Allergy and Infectious Diseases
- Multifunctional Analysis of Antigen-Specific T Cells: Correlates of Vaccine Efficacy

Abraham Lee, University of California, Irvine
- Novel microfluidic technologies for portable diagnostics systems

Adrian Ozinsky, Institute for Systems Biology
- Can parallel single cell assays support diagnostics in tuberculosis?

Late Breakers

Pernille Ravn
Improving blood based assays for the diagnosis of active and latent TB infection using IP10; Preliminary data from HIV positive TB patients and children with LTBI

Beate Kampmann
Immune responses to mycobacteria in immunocompetent and immunocompromised children

Françoise Mascart
HBHA-induced interferon-gamma release assay for the diagnosis of both latent and active tuberculosis

Karen Steingart and Suman Laal
Serodiagnosis of TB: 1. A meta-analysis of the performance of purified antigens of M. tuberculosis and 2. Synthetic peptides of new specific cell-wall proteins for TB diagnosis